Improvement of Dissolution Rate of Gliclazide Through Sodium Salt Formation
نویسندگان
چکیده
منابع مشابه
Dissolution rate enhancement of gliclazide by ordered mixing.
The poorly water soluble antidiabetic drug gliclazide was selected to study the effect of excipients on dissolution rate enhancement. Ordered mixtures of micronized gliclazide with lactose, mannitol, sorbitol, maltitol and sodium chloride were prepared by manual shaking of glass vials containing the drug and excipient(s). Different water soluble excipients, addition of surfactant and superdisin...
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ژورنال
عنوان ژورنال: Dissolution Technologies
سال: 2014
ISSN: 1521-298X
DOI: 10.14227/dt210414p49